Placenta tissue - a precious source

Placenta Tissue

Stem cells from the placenta are of significant value. Placental tissue is stored unmanipulated as the original tissue. The number of clinical studies in which stem cells from the placenta are used is constantly increasing. They are mainly used for neurological diseases (autism, cerebral palsy), MS, stroke, but also for diabetes.

Special characteristics of stem cells from placenta tissue

  1. Stem cells from placenta tissue have very powerful properties. The placenta is a tissue source that contains several different cell types in large quantities, which still receive less attention today, but could be of therapeutic relevance in the future.
  2. Stem cells from placenta tissue have a strong immune tolerance. The stem cells have a high degree of viability and a low risk of contamination. In addition, these cells can be used to a wider range, even if the tissue characteristics within the family do not match perfectly.
  3. Stem cells from placenta tissue have a high repair potential. Thanks to their high reproductive capacity, stem cells from the placenta are used in regenerative medicine, for example, to repair injured or diseased tissue.

Stem cells from the placenta are a highly potential source for medical therapies due to their ability to differentiate into different cell types and treat diseases while eliciting a minimal rejection response in the body.

The promising future of placenta stem cells

As VITA 34, we are responding to the extremely active research and growing application environment in the therapeutic use of postnatal cells and would like to provide our customers with the widest possible range of storage options.

The increasing number of applications for cell therapies in personalized and regenerative medicine is also reflected in the steady rise in the number of product approvals. In the past three years, the number of authorized products has doubled.

This rapidly increasing number of cell therapy treatment options is contrasted by the fact that the placental cellular material generated at birth is discarded as medical waste according to conventional guidelines and is no longer available for future potential applications. We at VITA 34 would like to counteract this situation and, in addition to the storage of umbilical cord blood and cells from umbilical cord tissue, which has been established for many years, now also offer you the possibility to store placental tissue of your newborn child in a cryogenic way.

More about the topic

Placenta tissue - a precious resource of inestimable value

Stem cells from the placenta are of great value - for example in regenerative medicine.

Umbilical cord tissue - rich in valuable stem cells

This umbilical cord tissue contains a particularly large number of mesenchymal stem cells and is therefore also of interest for stem cell therapy.

Advantages and special properties of umbilical cord blood

The stem cells from umbilical cord blood are unique, young and particularly adaptable. Stored umbilical cord blood can therefore be used in stem cell therapies.

Storing umbilical cord blood - safely with Vita 34

We have developed reliable processes and safe materials for the storage of stem cells so that they will be available to your child in the best quality for many years to come.

Did you know…?

In order to be able to deal with the topic in more detail, we would like to draw your attention to two scientific review articles on the therapeutic potential of cells isolated from the placenta. Among other things, these articles describe the different areas of the placenta for the isolation of (stem) cells, the cell types into which these cells can be differentiated, or which other properties (e.g. the secretion of signaling substances) these cells and tissues possess. We have briefly summarized the main statements in the publications for you as follows and supplemented the content for a better understanding. You can view the original publications at any time under the link.

Perinatal tissues and cells in tissue engineering and regenerative medicine

Perinatal placental tissues are a rich source of human extracellular matrix proteins, growth factors and stem cells with demonstrated potential for use in a variety of therapeutic applications. Due to their placental origin, these tissues have unique biological properties, including angiogenic, anti-inflammatory, antifibrotic, antimicrobial and immunoprivileged properties. In addition, as a temporary organ, the placenta is usually disposed of as medical waste and thus represents a readily available, inexpensive, "unlimited" and ethically acceptable source of raw materials. Although some of these tissues, such as the amniotic membrane and the umbilical cord, are used in clinical practice, most of them are still hardly researched nor used in practice. The aim of this review is to outline and highlight the most relevant applications of perinatal tissues as a source of biomaterials and stem cells in the therapeutically promising fields of tissue engineering and regenerative medicine (TERM). It will also show how these approaches can help overcome the lack of suitable scaffold materials. It will also show how these approaches can be used to overcome the lack of suitable scaffold materials and cell sources that currently limit the translation of TERM strategies into clinical applications.

Authors: Inês A. Deus, João F. Mano, Catarina A. Custódio; Department of
Chemistry, University of Aveiro, Campus Universitário de Santiago, 3810-193
Aveiro, Portugal
Source: Acta Biomaterialia 2020, 110, 1-14


Click here for original publications!

Current status and future prospects of perinatal stem cells

The placenta is a temporary organ that is discarded as medical waste after birth and at the same time one of the most interesting organs with promising diverse cell and tissue sources for use in regenerative medicine and tissue engineering, both in experimental and clinical settings. The placenta has unique intrinsic properties because it has to fulfill many different roles during pregnancy: it is formed by cells from two individuals (mother and fetus). It contributes to the development and growth of a "non-autologous/alien" (allogeneic) fetus and has two independent and interacting circulatory systems. Various progenitor and stem cell types, as well as different perinatal tissues, can be isolated from the placenta, making it a particularly interesting candidate for use in cell therapy and regenerative medicine. The primary source of perinatal progenitor cells is umbilical cord blood. Cord blood has been known as a source of hematopoietic stem/progenitor cells since 1974. Umbilical cord blood stored in biobanks has been used for over 30 years to treat various hematologic and immunologic diseases. Other perinatal tissues that are routinely discarded as medical waste contains other cells with high potential therapeutic value. In fact, mesenchymal stromal cells are most commonly used in clinical trials of perinatal cell therapies. In this review article, we look at the different perinatal tissues and the different isolated perinatal stem cells in turn, with their phenotypic characteristics and the preclinical use of these cells in numerous pathologies. An overview of the clinical applications of perinatal cells is also given, with particular emphasis on the clinical studies leading to the treatment of COVID-19 related pneumonia. In addition, we describe the use of new technologies in the field of perinatal stem cells and the future directions and challenges of this fascinating and rapidly advancing field of perinatal cells and regenerative medicine.

Authors: Paz de la Torre and Ana I. Flores, Grupo de Medicina
Regenerativa, Instituto de Investigación Sanitaria Hospital 12 de Octubre
(imas12), Avda.
Source: Genes 2021, 12, 6


Click here for original publications!

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As a precaution, store either the umbilical cord blood or the umbilical cord tissue after the birth of your child. We offer both at different prices and terms. 

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Storing cord blood and cord tissue

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Our guidebook for parents contains comprehensive information on the subject of stem cell storage. Order the guidebook by mail at no charge and without any obligation.

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